Welcome to the Smrcka Lab

Our laboratory studies mechanisms for cellular communication via G protein coupled receptors (GPCRs).  The GPCR superfamily includes receptors for adrenaline, serotonin, acetylcholine taste molecules, smell, and even light!  They are the largest family of cell surface receptors and 30-40% of marketed drugs target GPCRs.  Our laboratory uses a wide variety of methods to study the involvement of these receptors in physiology and disease.  We provide a dynamic environment where trainees can gain experience in a wide repertoire of methods applied to important biological problems. Learn more »


December 2019: Wenhui passed her qualifying exam.  Congratulations!!
October 2019: Isaac Fisher successfully defended his Ph.D. Thesis!  Congratulations!!
September 2019:  Congratulations Naincy for winning a “Best Poster” award at the Department of Pharmacology retreat.
August 2019: Craig and Wei’s cofirst author paper was published in eLife “Golgi localized b-adrenergic receptors stimulate Golgi PI4P hydrolysis by PLCe to regulate cardiac hypertrophy”
July 2019: Naincy was awarded the Pharmacology Centennial Fund Predoctoral Fellowship.
June 2019: Hoa was awarded the 2019 Upjohn Postdoctoral Fellowship.
April 2019: Tyler successfully passed his qualifying exam.  Congratulations!